OPTYGEN HP
CLINICALLY PROVEN ENDURANCE FORMULA
Our premium legal, safe and stimulant-free formula that’s engineered to increase endurance and performance. Studies on endurance athletes who used OptygenHP had a 42% increase in time to lactate threshold, a 26% reduction in cortisol and a significant improvement in endurance capacity.
✓ Maximizes oxygen utilization & VO2 max
✓ Optimizes ATP production
✓ Reduces & buffers lactic acid
CUSTOMER REVIEWS
Daniel
GAME CHANGER
"Quite literally a game changer for endurance, athletes looking to optimize their performance gains"
Mary U.
BREAKTHROUGH YEAR!
"I immediately saw the difference in training my heart rate dropped significantly, and I was able to push harder at a lower heart rate"
Joshua A.
BIG GAINS FAST
"I increased my VO2 max by five points in the first 10 weeks"
THE POWER TO ENDURE
IMPROVES POWER OUTPUT & ANAEROBIC CAPACITY
OptygenHP’s clinically effective dose of beta-alanine helps improve power and strength during intense exercise. This makes it especially useful for activities like sprints, cycling, or rowing, where pushing through fatigue is key. Beta-alanine also boosts endurance, helps with repeated bursts of effort, and can reduce the feeling of exhaustion during workouts.
OptygenHP gives my body the extra support it needs to perform in training and racing.
LIKE NOTHING ELSE
"OptygenHP is unlike anything else on the market. To have a supplement that helps you adapt to the stress of huge training and race loads is a big help. I've used it in every Grand Tour.”
– Larry Warbasse (professional cyclist)
GO. RECOVER. GO AGAIN.
BOOSTS RECOVERY AND GLYCOGEN SUPPLY
Clinical studies show that the Senactiv® in OptygenHP also decreases exercise-induced muscle damage and reduces post-exercise inflammation by supporting autophagy, the process of your body clearing damaged cells and proteins in order to help recovery and drive training adaptations. More efficient recovery; faster return to form between workouts and races.
GO. RECOVER. GO AGAIN.
BOOSTS RECOVERY AND GLYCOGEN SUPPLY
Clinical studies show that the Senactiv® in OptygenHP also decreases exercise-induced muscle damage and reduces post-exercise inflammation by supporting autophagy, the process of your body clearing damaged cells and proteins in order to help recovery and drive training adaptations. More efficient recovery; faster return to form between workouts and races.
PUSH YOURSELF FURTHER
IMPROVES TIME TO EXHAUSTION
OptygenHP contains a patented ingredient, Senactiv®, that has been scientifically validated in human studies to extend high-intensity exercise performance by up to 20% while also tripling muscle glycogen accumulation rate during the three hours following high-intensity exercise.
You’ll have more reserves for the finale and less downtime between intervals – or while responding to attacks. Find another effort in yourself, sooner, and race like the next gap will be the one that sticks.
PUSH YOURSELF FURTHER
IMPROVES TIME TO EXHAUSTION
OptygenHP contains a patented ingredient, Senactiv®, that has been scientifically validated in human studies to extend high-intensity exercise performance by up to 20% while also tripling muscle glycogen accumulation rate during the three hours following high-intensity exercise.
You’ll have more reserves for the finale and less downtime between intervals – or while responding to attacks. Find another effort in yourself, sooner, and race like the next gap will be the one that sticks.
RISE TO THE CHALLENGE
THE SHERPAS' PERFORMANCE SECRET
OptygenHP’s advanced formula blends Ashwagandha, Cordyceps, and Rhodiola—adaptogens first used by Tibetan Sherpas to help them endure the extreme physical demands and low oxygen conditions of Everest’s highest altitudes.
Clinical research shows these adaptogens are ideal for athletes. Their benefits include improved oxygen efficiency, increased time to exhaustion, reduced fatigue, and more efficient energy production. In short, adaptogens improve endurance performance.
TEST YOUR LIMITS
SHATTER THE GLASS CEILING
OptygenHP maximizes athletic performance. Powered by clinically proven adaptogens, it enhances aerobic capacity, increases VO2 max, and reduces fatigue so you can train harder and perform at a higher level.
TEST YOUR LIMITS
SHATTER THE GLASS CEILING
OptygenHP maximizes athletic performance. Powered by clinically proven adaptogens, it enhances aerobic capacity, increases VO2 max, and reduces fatigue so you can train harder and perform at a higher level.
NEXT-LEVEL PERFORMANCE
THE ENERGY YOU NEED, FASTER & MORE EFFICIENTLY
OptygenHP’s proprietary ATPro™ matrix of five key nutrients is engineered to optimize ATP production—the body’s primary energy source. By increasing ATP, athletes can sustain performance for longer periods, delaying the onset of fatigue so you can train harder, more frequently, with less fatigue.
GET THE MOST OUT OF EVERY EFFORT
BOOSTS RECOVERY AND GLYCOGEN SUPPLY
Endurance training pumps additional cortisol, the primary stress hormone, into your system, which negatively impacts motivation, sleep, and the immune system. Chronically elevated cortisol also inflicts a penalty on performance, workload, and recovery by suppressing testosterone levels and dropping the panicked body into a catabolic state, which involves metabolizing muscle while storing fat. When we say “overtraining,” this is what we mean.
A clinical study showed OptygenHP reduced post-exercise levels of cortisol by 26%. By modulating cortisol, athletes experience better recovery, an increase in VO2, improved oxygen utilization and enhanced performance. When every session is critical, OptygenHP ensures you’re getting maximum returns without the risk of overtraining.
GET THE MOST OUT OF EVERY EFFORT
BOOSTS RECOVERY AND GLYCOGEN SUPPLY
Endurance training pumps additional cortisol, the primary stress hormone, into your system, which negatively impacts motivation, sleep, and the immune system. Chronically elevated cortisol also inflicts a penalty on performance, workload, and recovery by suppressing testosterone levels and dropping the panicked body into a catabolic state, which involves metabolizing muscle while storing fat. When we say “overtraining,” this is what we mean.
A clinical study showed OptygenHP reduced post-exercise levels of cortisol by 26%. By modulating cortisol, athletes experience better recovery, an increase in VO2, improved oxygen utilization and enhanced performance. When every session is critical, OptygenHP ensures you’re getting maximum returns without the risk of overtraining.
“Utilization of OptygenHP proves beneficial to trained athletes undergoing high training volumes by decreasing baseline stress and improving training sessions, leading to an overall improvement in performance."
- Excerpt from a pilot study conducted by Dr. Andrew Creer of South Dakota State University
THIS IS WHAT “FINDING ANOTHER GEAR” LOOKS LIKE
CLINICALLY SHOWN TO INCREASE LACTATE THRESHOLD
OptygenHP’s adaptogen blend weaponizes the lactic acid that accumulates in muscles as exercise output outpaces oxygen intake and energy metabolism goes anaerobic. In a clinical study, adaptogens in the OptygenHP formula increased time to the lactate threshold by 42%, even in highly trained distance runners.
In real world terms, that’s about five additional seconds before threshold: 13.9 seconds versus 18.1. That can make all the difference during repeated attacks or when the elastic is stretching and every moment could see it snap. OptygenHP turns the lactate threshold into an opportunity for you – and an even bigger weakness for your competition.
THIS IS WHAT “FINDING ANOTHER GEAR” LOOKS LIKE
CLINICALLY SHOWN TO INCREASE LACTATE THRESHOLD
OptygenHP’s adaptogen blend weaponizes the lactic acid that accumulates in muscles as exercise output outpaces oxygen intake and energy metabolism goes anaerobic. In a clinical study, adaptogens in the OptygenHP formula increased time to the lactate threshold by 42%, even in highly trained distance runners.
In real world terms, that’s about five additional seconds before threshold: 13.9 seconds versus 18.1. That can make all the difference during repeated attacks or when the elastic is stretching and every moment could see it snap. OptygenHP turns the lactate threshold into an opportunity for you – and an even bigger weakness for your competition.
"With OptygenHP, my capacity to handle a massive training load and then absorb and improve is noticeable."
A LEAN MACHINE
REDUCES FAT, PRESERVES MUSCLE
Regulating insulin, metabolizing glucose, mobilizing fatty acids for fuel – OptygenHP’s biologically active chromium touches on virtually every aspect of getting grist to the mill of cellular energy production.
It meters the delivery of calories to sustain a steady energy supply, and your body doesn’t have to pull as much fuel from your muscles – both during exercise and daily life – so you’re also building a leaner, more competition-tuned body composition, all year long.
RESEARCH
Optygen works on three different levels all working synergistically with the goal of increasing endurance. Endurance is defined as your ability to perform work over a period of time where there is oxygen delivered to the muscles. There are three critical components necessary to increase your endurance capacity.
1. EFFICIENT OXYGEN TRANSFER
Rhodiola and Cordyceps are the key ingredients in Optygen. Clinical research on elite athletes has shown both these adaptogenic herbs increase oxygen utilization, increase the body’s ability to adapt to high levels of physical stress, increase anaerobic threshold and reduce lactic acid. These herbs are both found and cultivated in Tibet. Clinical studies on Cordyceps have shown it increases endurance. In a 1998 study, Dr. Edmond Burke demonstrated how these two adaptogenic herbs improve the efficiency of oxygen transfer in the cell leading to improvements in oxygen uptake and VO2max.
2. ATP PRODUCTION
Endurance athlete’s VO2max is directly proportional to their ability to efficiently produce Adenosine Triphosphate (ATP). Clinical research has shown that endurance athletes diminish their ATP stores in exhaustive exercise, which can lead to a reduction in aerobic metabolism and endurance. Since ATP is the final step in aerobic energy production, it’s critical that the nutrients feeding the ATP cycle are readily available. Calcium pyruvate, sodium phosphate, potassium phosphate, adenosine and d-ribose all play critical roles in glycolysis and the citric acid cycle, leading to efficient ATP production. Optygen’s proprietary ATPro™ matrix of five key nutrients is designed to assure ATP production.
3. EFFICIENT GLUCOSE METABOLISM
The Optygen formula utilizes chromium for its ability to break down fuel. Chromium is an essential trace mineral that aids in glucose metabolism, regulation of insulin levels, and maintenance of healthy blood levels of cholesterol and other lipids. Chromium forms part of a compound in the body known as Glucose Tolerance Factor (GTF), which is involved in regulating the actions of insulin in maintaining blood sugar levels and, possibly, in helping to control appetite. It’s critical that any drink, bar or meal consumed prior to a race or exercise gets broken down efficiently in order to maximize your fuel delivery. Insulin spikes or lack of insulin response can cause the nutrients to either be rushed into your bloodstream too quickly or not quickly enough. Chromium regulates this nutrient breakdown so you have equal and sustained nutrient delivery to the working muscles.
Q&A
Q: How is this OptygenHP formula different than the previous formula?
A: This formula contains the adaptogenic herb ashwagandha. Research shows ashwaganda improves VO2max, modulates cortisol and increases work output. We have substituted 150mg of Rhodiola with 150mg of ashwagandha. The formula delivers 150mg Rhodiola, 150mg ashwagandha, 800mg cordyceps, 200mcg chromium, 50mg ActiGin and our proprietary ATPro matrix.
Q: Why are the capsules red?
A: The capsules are dark red to further reduce UV light degradation ensuring the highest quality, potency, and purity.
Q: How will OptygenHP help me race better?
A: This formula will dramatically improve your training and recovery. It’s designed to help you through your most intense training and racing. Research has shown the following endurance benefits:
Increases Endurance and PerformanceReduced Lactic Acid
Increases oxygen utilization
Increase in VO2 Max
Increase in Time to Exhaustion
Increase Anaerobic threshold
Improved exercise capacity
Increase Maximal Oxygen uptake
30% – 50% increase in Oxygen Utilization
Increase ratio of ATP by 45% – 55%
Enhanced Endurance
Increase in ATP production
Q: How do I maximize the benefits?
A: For best results, use OptygenHP during all your intense training and racing. This will allow you to train at a higher level by improving the body’s ability to adapt to physical stress, increasing anaerobic threshold and reducing lactic acid. These improvements will help you race at a higher level. For best results, you should use OptygenHP consistently for many months. If you start taking it a week before a race, benefits will be minimal.
Q: Should I take OptygenHP every day?
A: Yes, it’s important to take OptygenHP daily, even on days you are not training or racing. If you don’t take it every day, you will not experience the full potential.
Q: Can I give my son and daughter Optygen or OptygenHP?
A: Because there haven't been any published clinical studies on people under 18, we do not recommend Optygen or OptygenHP to athletes who are under 18 years of age.
Q: How long will it take before I start noticing the benefits?
A: You should start experiencing the benefits of OPTYGEN approximately six (6) days after you start taking OPTYGEN.
Q: Why is the bottle glass instead of plastic?
A: OPTYGEN is packaged in an amber glass bottle. Unlike plastic bottles, amber glass is an impermeable barrier that protects the product from harmful UV light and oxygen degradation.
Q: Why does OPTYGEN have Cordyceps and Rhodiola Rosea?
A: OPTYGEN utilizes two adaptogens that are the primary ingredients in the formulation. Patented Rhodiola Rosea and Cordyceps are both found and cultivated in Tibet. Both these herbs play critical roles in allowing the body to adapt to high levels of physical stress (similar to the stress a body is subject to when climbing Everest). It’s these adaptations to hypoxia (lack of oxygen) which led researchers to also test its effects on elite endurance athletes. Both Rhodiola and Cordyceps have been clinically shown to increase VO2Max, lung function, oxygen utilization and anaerobic threshold significantly.
Q: How should I use Optygen?
A: For best results, use Optygen during all intense training. Optygen will allow you to train at a higher level by improving the body’s ability to adapt to physical stress, increasing aerobic threshold and reducing lactic acid. These improvements will help you race at a higher level. For best results, Optygen should be used consistently for many months. If you start taking Optygen a week before a race, benefits will be minimal.
Q: What is Beta-Alanine and how does it work?
A: Beta-Alanine is an amino acid that interacts directly with the amino acid carnosine to buffer lactic acid. With intense training, you can increase your carnosine levels with a limiting factor: the body cannot produce enough Beta-Alanine to allow the body to continue to increase carnosine levels. Clinical studies show that supplementing with Beta-Alanine allows the body to produce significantly higher carnosine levels. The result is a highly effective mechanism for the metabolism of lactate, which in-turn improves endurance capacity.
Q: What are the benefits of taking Beta-Alanine?
A: Cutting edge human clinical studies show Beta-Alanine supplementation:Significantly improves muscular endurance.Improves exercise capacityIncreases Total Work Done by 13%Boosts strength Increases endurance capacityEnhances Ventilatory ThresholdDelays onset of neuromuscular fatigue
Q: Is the OptygenHP formula legal?
A: Absolutely. First Endurance has taken additional measures to ensure that our products are safe, legal and stimulant free. First Endurance supplements are legal to use in any sporting event governed by the World Anti-Doping Association (WADA), the US anti-doping association (USADA) and by the UCI (Union Cycliste International), US Cycling, International Cycling, US Triathlon and International Triathlon. Some commonalties among these governing bodies include banned substances which fall into one or more of the following categories as listed in Section I A-E of the UCI Prohibited Classes of substance and Prohibited Methods document. A) Stimulants B) Narcotics C) Anabolic agents D) Diuretics and E) Peptide hormones, mimetics and analogues. This document goes on to list banned substances within each of these classes. Regulations also ban ‘Compounds chemically or pharmacologically related to the products mentioned’. OptygenHP contains NO ingredients, which are explicitly listed under the banned substance list, nor are any of the ingredients related chemically or pharmacologically. First Endurance has also contacted the USADA and received verbal confirmation that our ingredients are not banned based on their regulations. Note: USADA, WADA and UCI do not offer any certification or written confirmation. First Endurance manufactures its formulations to the highest GMP (Good Manufacturing Practice) standards available. In addition we use a proprietary manufacturing method for added safety and assurance. Following the Supplement Facts panel you will notice we list ‘NO processing aids’ under Other Ingredients. The only ingredients found in this formulation, are those listed in the Supplement Facts Panel.Part XIV Article 7 of the Anti-doping Examination Regulations contains the following warning: riders must refrain from using any substance, foodstuff or drink of which they do not know the composition. It must be emphasized that the composition indicated on a product is not always complete. The product may contain prohibited substances not listed in the composition.
Q: Will OptygenHP help me recover faster?
A: Yes, it will help you recover. Because this formula was developed to help you adapt during times of maximum stress, it also aids in recovery.
Q: Should I ‘cycle’ on and off with Optygen/OptygenHP?
A: Great question. Both these products work best when you are ‘stressed’, so use the product during stressful training. The cycling period should parallel your training program. In other words, you should be using Optygen/OptygenHP consistently through all hard training blocks/months and go off anytime you have a break or downtime. For some, this means being on the product through most if not all the racing season. For others, it might mean cycling off for a week once every 4-6 weeks.